Pseudomonas Exotoxin A: optimized by evolution for effective killing

Pseudomonas Exotoxin A: optimized by evolution for effective killing

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Pseudomonas Exotoxin A (PE) is the most toxic virulence factor of the pathogenic bacterium Pseudomonas aeruginosa.This review describes current knowledge about the intoxication pathways AEG DCK431110M Multifunction Built In Stainless Steel Electric Double Oven of PE.Moreover, PE represents a remarkable Vacuum Bag Slide example for pathoadaptive evolution, how bacterial molecules have been structurally and functionally optimized under evolutionary pressure to effectively impair and kill their host cells.